Source · Prevention of Future Deaths

Brian Jackson

Ref: 2021-0246 Date: 16 Jul 2021 Coroner: David Lewis Area: Liverpool and Wirral Responses identified: 1 / 2 View PDF

Delirium symptoms were missed due to reliance on a flawed CAM-ICU assessment tool, especially for certain presentations, risking suboptimal diagnosis and treatment for patients nationwide.

Date 16 Jul 2021
56-day deadline 8 Sep 2021
Responses identified 1 of 2
Hospital Death (Clinical Procedures and medical management) related deaths

Coroner's concerns

AI summary
Delirium symptoms were missed due to reliance on a flawed CAM-ICU assessment tool, especially for certain presentations, risking suboptimal diagnosis and treatment for patients nationwide.
View full coroner's concerns
The MATTERS OF CONCERNS are as follows: Following major heart surgery the Deceased spent a week on the Post-Operative Critical Care Unit, during which he presented intermittently with a range of symptoms which I was told in evidence constituted delirium, but were not consistently recognised or diagnosed as such by hospital staff. These symptoms were variously described as including confusion, agitation, severe paranoia and anxiety. On a number of occasions the Deceased’s was assessed using the tool known as CAM-ICU, which I heard is a nationally recognised diagnostic tool, in widespread use across the country. ON each occasion the result was negative for the purpose of delirium diagnosis, contradicting the view expressed in court to the effect that a diagnosis of delirium was appropriate. The hospital had its own policy concerning the management of patients at risk of delirium, the use of which depended in large measure upon a diagnosis being made. My impression was that the CAM-ICU results relied too heavily upon whether the patient was orientated in time and place, without allowing for a more complex cocktails of presentational symptoms to be taken into account. I was told by senior hospital staff that their investigation has revealed shortcomings in the efficacy of the CAM-ICU tool, notably in assessing the risk faced by patients with ‘hypo symptoms’ of delirium, or patients who produce a negative CAM-ICU result but present with edidence of paranoia. I heard details of extensive changes made by the hospital in its local arrangements and also that the hospital had approached NICE to ask if the CAM-ICU tool itself could be modified to take account of the lessons it had learnt in this case. I was told that the response from NICE was that use of the tool (and NICE guidance around this subject) had only recently been reviewed, in 2019, and is not to be reviewed again for some time. I am concerned that across the country an assessment tool remains in widespread use despite the problems identified and is likely to remain so for the indefinite future, meaning that patients at risk of delirium are not diagnosed or treated optimally. The outcome of this cases illustrates the gravity of the harm that can result.

Responses

1 respondent
National Institute for Health and Care Excellence Other
6 Sep 2021 PDF
Action Planned

NICE acknowledges concerns and will consider them during an update to its guideline on delirium, focusing on risk assessment and diagnosis, including in ICU settings. (AI summary)

View full response
Dear Mr Lewis,

I write in response to your correspondence, sent to NICE on 19 July 2021, regarding the very sad death of Mr Brian Jackson. I would like to express my sincere condolences to his family.

We have reflected on the circumstances surrounding Mr Jackson’s death, and the concerns raised in your report.

In our guideline on delirium: prevention, diagnosis and management [CG103] we recommend that all people in hospital should be observed, at least daily, for recent (within hours or days) changes or fluctuations in usual behaviour. If any of these behaviour changes is present, a healthcare professional who is trained and competent in the diagnosis of delirium should carry out a clinical assessment to confirm the diagnosis (see recommendation 1.4.1). Indicators of delirium are given in section 1.2 of the guideline and healthcare professionals are advised to be particularly vigilant for behaviour indicating hypoactive delirium.

For patients in critical care in whom indicators of delirium are identified, an assessment should be carried out using the confusion assessment method for ICU (CAM-ICU) and that this is undertaken by a healthcare professional who is trained and competent in the diagnosis of delirium (see recommendation 1.5.1).

Liverpool Heart and Chest Hospital informed us that they were undertaking a root cause analysis which was considering the ‘CAMS/ITU – RASS delirium risk assessment’. We advised them that we had recently completed a review of CG103 and that we were going to update the guideline, focusing on the risk assessment and diagnosis of delirium, including in ICU settings. We also advised how they could engage with the development process and send evidence to us for consideration during the update.

No diagnostic tool will ever be perfect, and during the development of the original guideline the committee prioritised a test that had high sensitivity and would ‘rule in’ patients with delirium.

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We will consider the issues you have raised in your report during the update of the guideline.

Report sections

Investigation and inquest
On 28/07/2020 I commenced an investigation into the death of Brian Jackson aged 64. The investigation concluded at the end of the inquest on 14 July 2021. The cause of death found was: I a Neck compression I b Ligature hanging I c
Circumstances of the death
Following major but successful heart surgery at Liverpool Heart and Chest Hospital, Thomas Drive, Broadgreen, Liverpool on16 July 2020 the Deceased developed symptoms consistent with delirium. On 23 July 2020 he was transferred from the Post-Operative Critical Care Unit to the Cedar Ward where (a few hours later) he used a ligature, which he had fashioned from pyjamas, to hang himself inside a locked bathroom. In doing so he sustained injuries from which he died at the scene, despite prompt medical attention.

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Report details

Reference
2021-0246
Date of report
16 July 2021
Coroner
David Lewis
Coroner area
Liverpool and Wirral

Responses identified

Responses identified 1 of 2
1 response not yet linked

Organisations named in PFD reports are normally expected to respond within 56 days. Deadline: 8 Sep 2021.

Sent to

Liverpool Heart and Chest Hospital
National Institute for Health and Care Excellence

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