Field safety notices - 21 March to 25 March 2016
A weekly index of the field safety notices manufacturers issued that week.
Source · Drug & device safety alerts
MHRA Drug & Device Safety Alerts
1,501 individual alerts
447 medicines recalls & defect notices
766 weekly / monthly index pages
Oct 2009 – Jul 2026
Drug safety updates, medicines recalls, device safety information and field safety notices published by the Medicines and Healthcare products Regulatory Agency. Source: MHRA alerts and recalls on GOV.UK.
Showing 2,267 publications of 2,267
Field safety notices - 14 March to 18 March 2016
A weekly index of the field safety notices manufacturers issued that week.
Field safety notices - 7 March to 11 March 2016
A weekly index of the field safety notices manufacturers issued that week.
Letters sent to healthcare professionals in February 2016
A periodic index page listing other alerts and letters, not a single alert.
Trametinib (Mekinist▼): risk of gastrointestinal perforation and colitis
An article in MHRA's monthly Drug Safety Update bulletin.
Field safety notices - 29 February to 4 March 2016
A weekly index of the field safety notices manufacturers issued that week.
Ambulatory syringe pumps (T34 and T60) and syringe extension sets used with the T34 pump, manufactured by Caesarea Medical Electronics (CME).
Maxolon 5mg/ml, solution for injection, 2ml ampoules PL 20072/0051
Field safety notices - 22 February to 26 February 2016
A weekly index of the field safety notices manufacturers issued that week.
Field safety notices - 15 to 19 February 2016
A weekly index of the field safety notices manufacturers issued that week.
Valproate and risk of abnormal pregnancy outcomes: new communication materials
An article in MHRA's monthly Drug Safety Update bulletin.
Letters sent to healthcare professionals in January 2016
A periodic index page listing other alerts and letters, not a single alert.
Field safety notices - 8 to 12 February 2016
A weekly index of the field safety notices manufacturers issued that week.
Field safety notices - 1 to 5 February 2016
A weekly index of the field safety notices manufacturers issued that week.
Class 2 medicines recall: Asda, St John’s Wort, HRI Good Mood and Superdrug St John’s Wort tablets THR 02231/0002
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Dotarem Solution for Injection, 15ml Syringe Gadoteric Acid 279.32 mg/ml (equivalent to 0.5mmol/ml) (CLDA) (16)A/01
Field safety notices - 25 to 29 January 2016
A weekly index of the field safety notices manufacturers issued that week.
Field safety notices - 18 to 22 January 2016
A weekly index of the field safety notices manufacturers issued that week.
Nicorandil (Ikorel): now second-line treatment for angina - risk of ulcer complications
An article in MHRA's monthly Drug Safety Update bulletin.
Letters sent to healthcare professionals in December 2015
A periodic index page listing other alerts and letters, not a single alert.
Levonorgestrel-releasing intrauterine systems: prescribe by brand name
An article in MHRA's monthly Drug Safety Update bulletin.
Field safety notices - 11 to 15 January 2016
A weekly index of the field safety notices manufacturers issued that week.
Field safety notices - 4 January to 8 January 2016
A weekly index of the field safety notices manufacturers issued that week.
Field safety notices - 28 December to 1 January 2016
A weekly index of the field safety notices manufacturers issued that week.
Field safety notices - 21 to 25 December 2015
A weekly index of the field safety notices manufacturers issued that week.
Syner-KINASE 10,000IU powder for solution for injection or infusion (CLDA (15)A/14)
Field safety notices - 14 to 18 December 2015
A weekly index of the field safety notices manufacturers issued that week.
Fludarabine 25mg/ml, 1 x 2ml - EBEWE Pharma Ges.m.g.h (CLDA (15) A/13)
Idarubicin 1mg/ml injection 5 and 10ml - Teva UK Limited (CLDA (15)A/12)
Medical device alerts archived in December 2015
A periodic index page listing other alerts and letters, not a single alert.
Specific batches of Omeprazole 20mg gastro-resistant capsules (hard) - capsule shells may be more brittle than normal
Antiretroviral medicines: updated advice on body-fat changes and lactic acidosis
An article in MHRA's monthly Drug Safety Update bulletin.
Bisphosphonates: very rare reports of osteonecrosis of the external auditory canal
An article in MHRA's monthly Drug Safety Update bulletin.
Thalidomide: reduced starting dose in patients older than age 75 years
An article in MHRA's monthly Drug Safety Update bulletin.
Mycophenolate mofetil, mycophenolic acid: new pregnancy-prevention advice for women and men
An article in MHRA's monthly Drug Safety Update bulletin.
Letters sent to healthcare professionals in November 2015
A periodic index page listing other alerts and letters, not a single alert.
Field safety notices - 7 to 11 December 2015
A weekly index of the field safety notices manufacturers issued that week.
Cardiac Resynchronization Therapy Pacing (CRT-P) - risk of loss of pacing therapy
Genotropin 5.3mg and 12mg powder for solution for injection (GoQuick pre-filled pen) - manufacturing defect of some pens used to administer somatropin
Mitoxantrone 2mg/ml Concentrate for Solution for Infusion - Hospira UK Limited
Field safety notices - 30 November to 4 December 2015
A weekly index of the field safety notices manufacturers issued that week.
Pioglitazone Accord 30mg Tablets - Accord Healthcare Limited (CLDA (15)A/10)
Field safety notices - 23 to 27 November 2015
A weekly index of the field safety notices manufacturers issued that week.
Cernevit powder for solution for injection or infusion - Baxter Healthcare Ltd (CDLA (15)A/09)
Field safety notices - 16 to 20 November 2015
A weekly index of the field safety notices manufacturers issued that week.
Field safety notices - 9 to 13 November 2015
A weekly index of the field safety notices manufacturers issued that week.
Letters sent to healthcare professionals in October 2015
A periodic index page listing other alerts and letters, not a single alert.
Vemurafenib (Zelboraf▼): risk of potentiation of radiation toxicity
An article in MHRA's monthly Drug Safety Update bulletin.
Crizotinib (Xalkori▼): risk of cardiac failure
An article in MHRA's monthly Drug Safety Update bulletin.
Field safety notices - 2 to 6 November 2015
A weekly index of the field safety notices manufacturers issued that week.
About this source
Individual alerts by type
Read the chart values
| Alert type | Individual alerts |
|---|---|
| Drug Safety Update | 713 |
| Class 1 Medicines Recall | 6 |
| Class 2 Medicines Recall | 159 |
| Class 3 Medicines Recall | 68 |
| Class 4 Medicines Defect Information | 179 |
| Company-Led Medicines Recall | 35 |
| Device Safety Information | 21 |
| Medical Device Alert | 40 |
| National Patient Safety Alert | 11 |
| MHRA Safety Roundup | 16 |
| Unclassified | 253 |
The MHRA regulates medicines and medical devices in the UK and publishes safety communications on GOV.UK in two streams: the monthly Drug Safety Update bulletin, and Alerts and recalls for drugs and medical devices. This page holds 2,267 of those publications, issued between October 2009 and July 2026.
MHRA classes a medicines recall by the hazard the defect presents: Class 1 life-threatening or serious, Class 2 could cause illness or mistreatment, Class 3 unlikely to cause harm, and Class 4 a caution in use rather than a recall, with the product staying available. A device notice is published as Device Safety Information, or, until 2021, as a Medical Device Alert.
What is not here. We hold each publication's title, type, date and link, not its text: read the alert on GOV.UK for the affected products and the actions MHRA asks for. An alert names a medicine or device and a clinical audience, not an organisation, so no alert on this page is linked to an NHS trust or other responsible body. The weekly “Field Safety Notices” pages are MHRA's own index of the notices manufacturers issued that week, not single alerts, and are counted separately above.