Field Safety Notice - 24 April to 28 April 2017
A weekly index of the field safety notices manufacturers issued that week.
Source · Drug & device safety alerts
MHRA Drug & Device Safety Alerts
1,501 individual alerts
447 medicines recalls & defect notices
766 weekly / monthly index pages
Oct 2009 – Jul 2026
Drug safety updates, medicines recalls, device safety information and field safety notices published by the Medicines and Healthcare products Regulatory Agency. Source: MHRA alerts and recalls on GOV.UK.
Showing 2,267 publications of 2,267
Recall of Human Albumin Biotest CLDA (17)A/02
Field Safety Notice - 18 April to 21 April 2017
A weekly index of the field safety notices manufacturers issued that week.
Ponatinib (Iclusig▼): risk of vascular occlusive events—updated advice on possible dose reduction
An article in MHRA's monthly Drug Safety Update bulletin.
Letters sent to healthcare professionals in March 2017
A periodic index page listing other alerts and letters, not a single alert.
Multiple sclerosis therapies: signal of rebound effect after stopping or switching therapy
An article in MHRA's monthly Drug Safety Update bulletin.
Valproate and developmental disorders: new alert asking for patient review and further consideration of risk minimisation measures
An article in MHRA's monthly Drug Safety Update bulletin.
Field Safety Notice - 10 April to 14 April 2017
A weekly index of the field safety notices manufacturers issued that week.
All Alaris™ GS, GH, CC, TIVA, PK, Enteral Syringe Pumps, and, Asena™ GS, GH, CC, TIVA, PK, Syringe Pumps – risk of uncontrolled bolus of medicine
Field Safety Notice - 03 April to 07 April 2017
A weekly index of the field safety notices manufacturers issued that week.
Comprehensive Reverse Titanium Shoulder Tray (specific lots) - risk of device fracture
Field Safety Notice - 27 March to 31 March 2017
A weekly index of the field safety notices manufacturers issued that week.
Class 2 Medicines Recall: Diclo-SR 75 Tablets (Diclofenac Sodium)
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Field Safety Notices - 20 March - 24 March 2017
A weekly index of the field safety notices manufacturers issued that week.
Launch of pilot reporting scheme for harms associated with illicit drugs, particularly new psychoactive substances
An article in MHRA's monthly Drug Safety Update bulletin.
SGLT2 inhibitors: updated advice on increased risk of lower-limb amputation (mainly toes)
An article in MHRA's monthly Drug Safety Update bulletin.
Field Safety Notices - 13 March - 17 March 2017
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices - 6 March - 10 March 2017
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices - 27 February - 3 March 2017
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices - 20 February - 24 February 2017
A weekly index of the field safety notices manufacturers issued that week.
Precautionary recall of Viridal Duo Powder and Solvent for Injection (EL (17)A/04)
Alaris® syringe pumps (GH, CC, TIVA & PK models) – risk of uncontrolled bolus of medicine.
Letters sent to healthcare professionals in January 2017
A periodic index page listing other alerts and letters, not a single alert.
Yellow Card reporting added to second clinical software system
An article in MHRA's monthly Drug Safety Update bulletin.
Hyoscine butylbromide (Buscopan) injection: risk of serious adverse effects in patients with underlying cardiac disease
An article in MHRA's monthly Drug Safety Update bulletin.
Field Safety Notices - 13 February - 17 February 2017
A weekly index of the field safety notices manufacturers issued that week.
Precautionary recall of Ergometrine Injections (CLDA (17)A/01)
Field Safety Notices - 6 February - 10 February 2017
A weekly index of the field safety notices manufacturers issued that week.
Oxylog 3000 and Oxylog 3000 plus ventilator – risk of failure
Field Safety Notices - 30 January - 3 February 2017
A weekly index of the field safety notices manufacturers issued that week.
Alka-Seltzer Original & Alka-Seltzer XS - recall of some batches due to an issue with the blister foil
Field Safety Notices - 23 January - 27 January 2017
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices - 16 January - 20 January 2017
A weekly index of the field safety notices manufacturers issued that week.
Direct-acting antiviral interferon-free regimens to treat chronic hepatitis C: risk of hepatitis B reactivation
An article in MHRA's monthly Drug Safety Update bulletin.
Apremilast (Otezla ▼): risk of suicidal thoughts and behaviour
An article in MHRA's monthly Drug Safety Update bulletin.
Letters sent to healthcare professionals in December 2016
A periodic index page listing other alerts and letters, not a single alert.
Intravenous N-acetylcysteine (NAC) for paracetamol overdose: reminder of authorised dose regimen; possible need for continued treatment with NAC
An article in MHRA's monthly Drug Safety Update bulletin.
Direct-acting antivirals to treat chronic hepatitis C: risk of interaction with vitamin K antagonists and changes in INR
An article in MHRA's monthly Drug Safety Update bulletin.
Field Safety Notices - 9 January - 13 January 2017
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices - 2 January - 6 January 2017
A weekly index of the field safety notices manufacturers issued that week.
Medical device alerts archived in January 2017
A periodic index page listing other alerts and letters, not a single alert.
Class 4 Caution in Use : Mirena 20 micrograms / 24 hours intrauterine delivery system
Field Safety Notices - 26 - 30 December 2016
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices - 19 December - 23 December 2016
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Caution in Use: Arava 10mg film-coated tablets (Leflunomide)
Field Safety Notices - 12 December - 16 December 2016
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Caution in Use: Amoxicillin Sugar Free Suspension 250mg/5ml & Amoxicillin Sugar Free Suspension 125mg/5ml
Field Safety Notices - 5 December - 9 December 2016
A weekly index of the field safety notices manufacturers issued that week.
Letters sent to healthcare professionals in November 2016
A periodic index page listing other alerts and letters, not a single alert.
Cobicistat, ritonavir and coadministration with a steroid: risk of systemic corticosteroid adverse effects
An article in MHRA's monthly Drug Safety Update bulletin.
About this source
Individual alerts by type
Read the chart values
| Alert type | Individual alerts |
|---|---|
| Drug Safety Update | 713 |
| Class 1 Medicines Recall | 6 |
| Class 2 Medicines Recall | 159 |
| Class 3 Medicines Recall | 68 |
| Class 4 Medicines Defect Information | 179 |
| Company-Led Medicines Recall | 35 |
| Device Safety Information | 21 |
| Medical Device Alert | 40 |
| National Patient Safety Alert | 11 |
| MHRA Safety Roundup | 16 |
| Unclassified | 253 |
The MHRA regulates medicines and medical devices in the UK and publishes safety communications on GOV.UK in two streams: the monthly Drug Safety Update bulletin, and Alerts and recalls for drugs and medical devices. This page holds 2,267 of those publications, issued between October 2009 and July 2026.
MHRA classes a medicines recall by the hazard the defect presents: Class 1 life-threatening or serious, Class 2 could cause illness or mistreatment, Class 3 unlikely to cause harm, and Class 4 a caution in use rather than a recall, with the product staying available. A device notice is published as Device Safety Information, or, until 2021, as a Medical Device Alert.
What is not here. We hold each publication's title, type, date and link, not its text: read the alert on GOV.UK for the affected products and the actions MHRA asks for. An alert names a medicine or device and a clinical audience, not an organisation, so no alert on this page is linked to an NHS trust or other responsible body. The weekly “Field Safety Notices” pages are MHRA's own index of the notices manufacturers issued that week, not single alerts, and are counted separately above.