Field Safety Notices: 18 to 22 March 2024
A weekly index of the field safety notices manufacturers issued that week.
Source · Drug & device safety alerts
MHRA Drug & Device Safety Alerts
1,501 individual alerts
447 medicines recalls & defect notices
766 weekly / monthly index pages
Oct 2009 – Jul 2026
Drug safety updates, medicines recalls, device safety information and field safety notices published by the Medicines and Healthcare products Regulatory Agency. Source: MHRA alerts and recalls on GOV.UK.
Showing 2,267 publications of 2,267
Field Safety Notices: 11 to 15 March 2024
A weekly index of the field safety notices manufacturers issued that week.
Counterfeits and unbranded copies of LifeVac anti-choking devices may fail to work correctly or worsen choking incidents if used, DSI/2024/003
Class 4 Medicines Notification: Fresenius Kabi Limited, Sodium Chloride Intravenous Infusion 0.9% Freeflex, EL (24)A/10
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Class 3 Medicines Recall: Besins Healthcare (UK) Ltd, Oestrogel Pump-Pack 750 micrograms/actuation Gel (estradiol), EL (24)A/09
MHRA class: the defect is unlikely to cause harm; recall is on other grounds.
MAGEC X System, NuVasive Specialized Orthopedics (NSO): UK suspension lifted, (DSI/2024/002)
Device Safety Information (DSI): MHRA advice on a device already in use.
Field Safety Notices: 4 to 8 March 2024
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices: 26 February to 1 March 2024
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices:19 to 23 February 2024
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Medicines Defect Information: Orifarm UK Ltd, Concerta XL 18mg & 36 mg prolonged release tablets, EL (24)A/07
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Class 2 Medicines Recall: Novartis Pharmaceuticals UK Limited, Adakveo 10 mg/ml concentrate for solution for infusion, EL(24)A/06
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Field Safety Notices: 5 to 9 February 2024
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices:12 to 16 February 2024
A weekly index of the field safety notices manufacturers issued that week.
Letters and medicine recalls sent to healthcare professionals in January 2024
A periodic index page listing other alerts and letters, not a single alert.
Codeine linctus (codeine oral solutions): reclassification to prescription-only medicine
An article in MHRA's monthly Drug Safety Update bulletin.
Pseudoephedrine: very rare risk of posterior reversible encephalopathy syndrome (PRES) and reversible cerebral vasoconstriction syndrome (RCVS)
An article in MHRA's monthly Drug Safety Update bulletin.
Class 3 Medicines Recall: Torrent Pharma (UK) Limited, Ramipril 1.25mg tablets, EL(24)A/05
MHRA class: the defect is unlikely to cause harm; recall is on other grounds.
Field Safety Notices: 29 January to 2 February 2024
A weekly index of the field safety notices manufacturers issued that week.
Paclitaxel coated devices (PCD) used in the treatment of peripheral arterial disease: update to previous MHRA guidance on use. Where indicated, PCD can be considered as a treatment option for both critical limb ischaemia (CLI) and intermittent claudication (IC) patients. (DSI/2024/001)
Device Safety Information (DSI): MHRA advice on a device already in use.
Class 4 Medicines Defect Information: Exeltis UK Limited, Gepretix 100mg Capsules, EL (24)A/04
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Field Safety Notices (FSNs) from 22 to 26 January 2024
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Medicines Defect Information: Cadila Pharmaceuticals (UK) Limited, Pantoprazole 40 mg Gastro-Resistant Tablets, EL (24)A/03
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Letters and medicine recalls sent to healthcare professionals in December 2023
A periodic index page listing other alerts and letters, not a single alert.
Fluoroquinolone antibiotics: must now only be prescribed when other commonly recommended antibiotics are inappropriate
An article in MHRA's monthly Drug Safety Update bulletin.
Valproate (Belvo, Convulex, Depakote, Dyzantil, Epilim, Epilim Chrono or Chronosphere, Episenta, Epival, and Syonell▼): new safety and educational materials to support regulatory measures in men and women under 55 years of age
An article in MHRA's monthly Drug Safety Update bulletin.
Field Safety Notices (FSNs) from 15 to 19 January 2024
A weekly index of the field safety notices manufacturers issued that week.
Omega-3-acid ethyl ester medicines (Omacor/Teromeg 1000mg capsules): dose-dependent increased risk of atrial fibrillation in patients with established cardiovascular diseases or cardiovascular risk factors
An article in MHRA's monthly Drug Safety Update bulletin.
Class 4 Medicines Defect Information: USV UK Limited, Sugammadex 100 mg/ml solution for injection (2 ml vial), EL(24)A/02
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Field Safety Notices (FSNs) from 8 to 12 January 2024
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices (FSNs) from 1 to 5 January 2024
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices (FSNs) from 25 to 29 December 2023
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Medicines Defect Information: Quadrant Pharmaceuticals Ltd, Cozaar 100mg film-coated tablets, EL(24)A/01
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Field Safety Notices (FSNs) from 18 to 22 December 2023
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices (FSNs) from 11 to 15 December 2023
A weekly index of the field safety notices manufacturers issued that week.
Aripiprazole (Abilify and generic brands): risk of pathological gambling
An article in MHRA's monthly Drug Safety Update bulletin.
Letters and medicine recalls sent to healthcare professionals in November 2023
A periodic index page listing other alerts and letters, not a single alert.
Vitamin B12 (hydroxocobalamin, cyanocobalamin): advise patients with known cobalt allergy to be vigilant for sensitivity reactions
An article in MHRA's monthly Drug Safety Update bulletin.
Class 3 Medicines Recall: Biocon Pharma UK Ltd., Posaconazole Biocon 100mg Gastro-resistant Tablets, EL(23)A/44
MHRA class: the defect is unlikely to cause harm; recall is on other grounds.
Class 4 Medicines Defect Information: Atnahs Pharma UK Limited, Clobazam Atnahs 5mg/5ml and 10mg/5ml Oral Suspension, EL(23)A/43
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Field Safety Notices: 4 to 8 December 2023
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Medicines Defect Information: Strandhaven Ltd t/a Somex Pharma, Tramadol Hydrochloride 50mg Capsules, Hard, EL (23)A/41
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Class 4 Medicines Defect Information: Strandhaven Ltd t/a Somex Pharma, Clarithromycin 250mg and 500mg film-coated tablets, EL (23)A/42
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Field Safety Notices: 27 November to 1 December 2023
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Medicines Notification: Teva UK Ltd., Caramet 25/100mg CR Tablets, EL(23)A/40
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Class 3 Medicines Recall: AstraZeneca UK Ltd., Fluenz Tetra nasal spray suspension, EL(23)A/39
MHRA class: the defect is unlikely to cause harm; recall is on other grounds.
Field Safety Notices: 20 to 24 November 2023
A weekly index of the field safety notices manufacturers issued that week.
National Patient Safety Alert: Valproate: organisations to prepare for new regulatory measures for oversight of prescribing to new patients and existing female patients (NatPSA/2023/013/MHRA)
A National Patient Safety Alert requires named actions from NHS providers.
Specific brands of carbomer eye gel: recall of AACARB eye gel, AACOMER eye gel and PUROPTICS eye gel: potential risk of infection, DSI/2023/11
E-cigarette use or vaping: reminder to remain vigilant for suspected adverse reactions and safety concerns and report them to the Yellow Card scheme
An article in MHRA's monthly Drug Safety Update bulletin.
Ozempic▼(semaglutide) and Saxenda (liraglutide): vigilance required due to potentially harmful falsified products
An article in MHRA's monthly Drug Safety Update bulletin.
About this source
Individual alerts by type
Read the chart values
| Alert type | Individual alerts |
|---|---|
| Drug Safety Update | 713 |
| Class 1 Medicines Recall | 6 |
| Class 2 Medicines Recall | 159 |
| Class 3 Medicines Recall | 68 |
| Class 4 Medicines Defect Information | 179 |
| Company-Led Medicines Recall | 35 |
| Device Safety Information | 21 |
| Medical Device Alert | 40 |
| National Patient Safety Alert | 11 |
| MHRA Safety Roundup | 16 |
| Unclassified | 253 |
The MHRA regulates medicines and medical devices in the UK and publishes safety communications on GOV.UK in two streams: the monthly Drug Safety Update bulletin, and Alerts and recalls for drugs and medical devices. This page holds 2,267 of those publications, issued between October 2009 and July 2026.
MHRA classes a medicines recall by the hazard the defect presents: Class 1 life-threatening or serious, Class 2 could cause illness or mistreatment, Class 3 unlikely to cause harm, and Class 4 a caution in use rather than a recall, with the product staying available. A device notice is published as Device Safety Information, or, until 2021, as a Medical Device Alert.
What is not here. We hold each publication's title, type, date and link, not its text: read the alert on GOV.UK for the affected products and the actions MHRA asks for. An alert names a medicine or device and a clinical audience, not an organisation, so no alert on this page is linked to an NHS trust or other responsible body. The weekly “Field Safety Notices” pages are MHRA's own index of the notices manufacturers issued that week, not single alerts, and are counted separately above.