Class 2 Medicines Recall: Boots Paracetamol 500 mg tablets (16s), EL(25)A/10
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Source · Drug & device safety alerts
MHRA Drug & Device Safety Alerts
1,501 individual alerts
447 medicines recalls & defect notices
766 weekly / monthly index pages
Oct 2009 – Jul 2026
Drug safety updates, medicines recalls, device safety information and field safety notices published by the Medicines and Healthcare products Regulatory Agency. Source: MHRA alerts and recalls on GOV.UK.
Showing 2,267 publications of 2,267
Class 2 Medicines Recall: Sun Pharmaceutical Industries Europe B.V., Pemetrexed 1000MG/100ML (10mg/ml) & 800MG/100ML (8mg/ml) Infusion bag, EL(25)A/09
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Class 3 Medicines Recall: Azacitidine 100 mg/vial and 150 mg/vial Powder for Suspension for Injection, EL(25)A/08
MHRA class: the defect is unlikely to cause harm; recall is on other grounds.
Letters and medicine recalls sent to healthcare professionals in January 2025
A periodic index page listing other alerts and letters, not a single alert.
Field Safety Notices: 17 to 21 February 2025
A weekly index of the field safety notices manufacturers issued that week.
Class 3 Medicines Recall: Glucophage SR 500 mg, 750mg and 1000mg Prolonged-release Tablets, EL(25)A/07
MHRA class: the defect is unlikely to cause harm; recall is on other grounds.
Field Safety Notices: 10 to 14 February 2025
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices: 3 to 7 February 2025
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Medicines Notification: Lansoprazole Gastro-resistant Hard Capsules 15mg, EL(25)A/06
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Class 2 Medicines Recall: Nitrofurantoin CNX Therapeutics 100 mg Prolonged-Release capsules, EL(25)A/05
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Field Safety Notices: 27 to 31 January 2025
A weekly index of the field safety notices manufacturers issued that week.
Class 2 Medicines Recall: Bristol Laboratories Limited, Amlodipine Bristol Lab 2.5 mg Tablets, EL (25)A/04
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Field Safety Notices: 20 to 24 January 2025
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices: 23 to 27 December 2024
A weekly index of the field safety notices manufacturers issued that week.
GLP-1 and dual GIP/GLP-1 receptor agonists: potential risk of pulmonary aspiration during general anaesthesia or deep sedation
An article in MHRA's monthly Drug Safety Update bulletin.
Letters and medicine recalls sent to healthcare professionals in December 2024
A periodic index page listing other alerts and letters, not a single alert.
Field Safety Notices: 13 to 17 January 2025
A weekly index of the field safety notices manufacturers issued that week.
UPDATE: Class 2 Medicines Recall: Tesco Health Dry Cough Relief 200ml, Asda Strong Dry Tickly Cough 200ml, Almus Dry Cough Relief & Bells Dual Action Dry Cough, EL(25)A/03
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Field Safety Notices: 21 to 25 August 2023
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices: 19 to 23 June 2023
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices: 6 to 10 January 2025
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Medicines Notification: Irbesartan 150 mg and 300 mg film-coated tablets, EL(25)A/02
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Class 4 Medicines Notification: Rabeprazole sodium 10mg and 20mg gastro-resistant tablets, EL(25)A/01
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Field Safety Notices: 30 December 2024 to 3 January 2025
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices: 16 to 20 December 2024
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices: 20 December 2024
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Medicines Notification: Argenx BV, Vyvgart 1000 mg solution for injection, EL (24)A/63
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Field Safety Notices: 9 to 13 December 2024
A weekly index of the field safety notices manufacturers issued that week.
Letters and medicine recalls sent to healthcare professionals in November 2024
A periodic index page listing other alerts and letters, not a single alert.
Field Safety Notices: 2 to 6 December 2024
A weekly index of the field safety notices manufacturers issued that week.
Class 2 Medicines Recall: Wockhardt UK Limited, WockAIR 160 microgram/4.5 microgram, inhalation powder, EL(24)A/62
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Field Safety Notices: 25 to 29 November 2024
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Medicines Defect Information: Brillpharma Limited, Oxybutynin hydrochloride Brillpharma 2.5 mg/5 ml Oral Solution, EL(24)A/61
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Class 3 Medicines Recall: Kent Pharma UK, Phenoxymethylpenicillin 250mg/5ml Oral Solution Sugar Free, EL (24)A/60
MHRA class: the defect is unlikely to cause harm; recall is on other grounds.
Class 4 Medicines Defect Information: Rosemont Pharmaceuticals Limited, Mycophenolate Mofetil 1g/5ml Oral Suspension, EL(24)A/59
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Class 4 Medicines Defect Information: Strides Pharma UK Ltd, Liothyronine Sodium 5 & 20 micrograms Tablets, EL(24)A/58
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Class 4 Medicines Defect Information: Morningside Healthcare Limited, Tramadol Hydrochloride 50 mg capsules & Tramadol Hydrochloride Morningside 50 mg Prolonged-Release capsules, EL(24)A/57
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Field Safety Notices: 25 November 2024
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices: 18 to 22 November 2024
A weekly index of the field safety notices manufacturers issued that week.
Class 3 Medicines Recall: Syri Limited, T/A SyriMed, Baclofen 10mg/5ml Oral Solution, EL(24)A/56
MHRA class: the defect is unlikely to cause harm; recall is on other grounds.
Field Safety Notices: 1 to 5 July 2024
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices: 11 to 15 November 2024
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Medicines Defect Information: Takeda UK Limited, Entyvio 108mg solution for injection in pre-filled syringe, EL(24)A/55
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Company led medicines recall: Leeds Trading Company LTC Ltd T/A LTC Healthcare, EXS Delay Spray Plus, CLMR(24)A/01
A recall the marketing authorisation holder initiated, published by MHRA.
Field Safety Notices: 4 to 8 November 2024
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Medicines Defect Information: Viatris UK Healthcare Ltd, Omeprazole 40 mg Powder for solution for infusion, EL(24)A/54
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Field Safety Notices: 8 November 2024
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Medicines Defect Information: Ennogen Healthcare Limited, Zoledronic Acid Ennogen 4mg/5ml concentrate for solution for infusion, EL (24)A/53
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Letters and medicine recalls sent to healthcare professionals in October 2024
A periodic index page listing other alerts and letters, not a single alert.
Field Safety Notices: 6 November 2024
A weekly index of the field safety notices manufacturers issued that week.
About this source
Individual alerts by type
Read the chart values
| Alert type | Individual alerts |
|---|---|
| Drug Safety Update | 713 |
| Class 1 Medicines Recall | 6 |
| Class 2 Medicines Recall | 159 |
| Class 3 Medicines Recall | 68 |
| Class 4 Medicines Defect Information | 179 |
| Company-Led Medicines Recall | 35 |
| Device Safety Information | 21 |
| Medical Device Alert | 40 |
| National Patient Safety Alert | 11 |
| MHRA Safety Roundup | 16 |
| Unclassified | 253 |
The MHRA regulates medicines and medical devices in the UK and publishes safety communications on GOV.UK in two streams: the monthly Drug Safety Update bulletin, and Alerts and recalls for drugs and medical devices. This page holds 2,267 of those publications, issued between October 2009 and July 2026.
MHRA classes a medicines recall by the hazard the defect presents: Class 1 life-threatening or serious, Class 2 could cause illness or mistreatment, Class 3 unlikely to cause harm, and Class 4 a caution in use rather than a recall, with the product staying available. A device notice is published as Device Safety Information, or, until 2021, as a Medical Device Alert.
What is not here. We hold each publication's title, type, date and link, not its text: read the alert on GOV.UK for the affected products and the actions MHRA asks for. An alert names a medicine or device and a clinical audience, not an organisation, so no alert on this page is linked to an NHS trust or other responsible body. The weekly “Field Safety Notices” pages are MHRA's own index of the notices manufacturers issued that week, not single alerts, and are counted separately above.