Source · Drug & device safety alerts
MHRA Drug & Device Safety Alerts
1,501 individual alerts
447 medicines recalls & defect notices
766 weekly / monthly index pages
Oct 2009 – Jul 2026
Drug safety updates, medicines recalls, device safety information and field safety notices published by the Medicines and Healthcare products Regulatory Agency. Source: MHRA alerts and recalls on GOV.UK.
Showing 2,267 publications of 2,267
Nutriflex Omega Special 2500ml: Company-led recall
Field Safety Notice - 13 August to 17 August
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notice - 6 August to 10 August
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notice - 30 July to 3 August
A weekly index of the field safety notices manufacturers issued that week.
Class 3 Medicines Recall: Sodium Cromoglicate eye drops and Murine Hayfever Relief eye drops (MDR 072-05/17)
MHRA class: the defect is unlikely to cause harm; recall is on other grounds.
Field Safety Notice - 23 to 27 July 2018
A weekly index of the field safety notices manufacturers issued that week.
Breast implants, all types, makes and models – Continue to report suspected cases of Breast Implant Associated - Anaplastic Large Cell Lymphoma (MDA/2018/027)
Medical Device Alert (MDA): the format MHRA used for device alerts until 2021.
Field safety notices - 16 to 20 July 2018
A weekly index of the field safety notices manufacturers issued that week.
Pressurised metered dose inhalers (pMDI): risk of airway obstruction from aspiration of loose objects
An article in MHRA's monthly Drug Safety Update bulletin.
Melatonin 10mg capsules: Company-led recall
Darunavir boosted with cobicistat: avoid use in pregnancy due to risk of treatment failure and maternal-to-child transmission of HIV-1
An article in MHRA's monthly Drug Safety Update bulletin.
Parenteral amphotericin B: reminder of risk of potentially fatal adverse reaction if formulations confused
An article in MHRA's monthly Drug Safety Update bulletin.
Letters sent to healthcare professionals in June 2018
A periodic index page listing other alerts and letters, not a single alert.
Medical Device Alerts issued in June 2018
A periodic index page listing other alerts and letters, not a single alert.
Eltrombopag (Revolade): reports of interference with bilirubin and creatinine test results
An article in MHRA's monthly Drug Safety Update bulletin.
Medicines taken during pregnancy: please report suspected adverse drug reactions, including in the baby or child, on a Yellow Card
An article in MHRA's monthly Drug Safety Update bulletin.
Field safety notices - 09 to 13 July
A weekly index of the field safety notices manufacturers issued that week.
Field safety notices - 28 May to 1 June 2018
A weekly index of the field safety notices manufacturers issued that week.
Class 1 Medicines Recall: Action Now – including out of hours Pharmacy Level Recall
MHRA class: the defect presents a life-threatening or serious risk to health.
Field safety notices - 2 to 6 July 2018
A weekly index of the field safety notices manufacturers issued that week.
Class 2 Medicines Recall: Fiasp FlexTouch 100 units/mL solution for injection pre-filled pen manufactured by Novo Nordisk (MDR 065-06/18)
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Field safety notices - 25 to 29 June 2018
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notice - 18 to 22 June 2018
A weekly index of the field safety notices manufacturers issued that week.
Denzapine 50mg/ml Oral Suspension - company led recall
Medical Device Alerts issued in May 2018
A periodic index page listing other alerts and letters, not a single alert.
Denosumab (Xgeva▼) for advanced malignancies involving bone: study data show new primary malignancies reported more frequently compared to zoledronate
An article in MHRA's monthly Drug Safety Update bulletin.
Letters sent to healthcare professionals in May 2018
A periodic index page listing other alerts and letters, not a single alert.
Denosumab (Xgeva▼) for giant cell tumour of bone: risk of clinically significant hypercalcaemia following discontinuation
An article in MHRA's monthly Drug Safety Update bulletin.
Dolutegravir (Tivicay▼, Triumeq▼, Juluca▼): signal of increased risk of neural tube defects; do not prescribe to women seeking to become pregnant; exclude pregnancy before initiation and advise use of effective contraception
An article in MHRA's monthly Drug Safety Update bulletin.
Field Safety Notice - 11 to 15 June 2018
A weekly index of the field safety notices manufacturers issued that week.
Class 2 Medicines Recall: Own-brand children’s glycerine and blackcurrant cough syrups manufactured by Bell, Sons & Co.
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Class 4 medicines defect information: Bleo-Kyowa®, Powder for Solution for Injection, 15,000 IU PL 16508/0046
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Field Safety Notice - 04 to 08 June 2018
A weekly index of the field safety notices manufacturers issued that week.
Field safety notices - 21 - 25 May 2018
A weekly index of the field safety notices manufacturers issued that week.
Valproate medicines (Epilim▼, Depakote▼): Pregnancy Prevention Programme materials online
An article in MHRA's monthly Drug Safety Update bulletin.
Field Safety Notice - 14 to 18 May 2018
A weekly index of the field safety notices manufacturers issued that week.
Letters sent to healthcare professionals in April 2018
A periodic index page listing other alerts and letters, not a single alert.
Medical Device Alerts issued in April 2018; recent alert about Accu-Chek blood glucose test strips
A periodic index page listing other alerts and letters, not a single alert.
Braltus (tiotropium): risk of inhalation of capsule if placed in the mouthpiece of the inhaler
An article in MHRA's monthly Drug Safety Update bulletin.
Gambro Ultrafilter U9000 microbial water filter – updated instructions due to leaks during use resulting in risk of hypovolemia.
Unlicensed Medicine Phenytoin 90mg/5ml Oral Suspension - company led recall
Field Safety Notice - 07 to 11 May 2018
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notice - 30 April to 04 May 2018
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notice - 9 to 13 April 2018
A weekly index of the field safety notices manufacturers issued that week.
Class 3 Medicines Recall: Latanoprost Timolol Eye drops
MHRA class: the defect is unlikely to cause harm; recall is on other grounds.
Field Safety Notice - 23 to 27 April 2018
A weekly index of the field safety notices manufacturers issued that week.
Letters sent to healthcare professionals in March 2018
A periodic index page listing other alerts and letters, not a single alert.
Medical Device Alerts issued in March 2018
A periodic index page listing other alerts and letters, not a single alert.
Suspect an adverse reaction? Yellow Card it!
An article in MHRA's monthly Drug Safety Update bulletin.
About this source
Individual alerts by type
Read the chart values
| Alert type | Individual alerts |
|---|---|
| Drug Safety Update | 713 |
| Class 1 Medicines Recall | 6 |
| Class 2 Medicines Recall | 159 |
| Class 3 Medicines Recall | 68 |
| Class 4 Medicines Defect Information | 179 |
| Company-Led Medicines Recall | 35 |
| Device Safety Information | 21 |
| Medical Device Alert | 40 |
| National Patient Safety Alert | 11 |
| MHRA Safety Roundup | 16 |
| Unclassified | 253 |
The MHRA regulates medicines and medical devices in the UK and publishes safety communications on GOV.UK in two streams: the monthly Drug Safety Update bulletin, and Alerts and recalls for drugs and medical devices. This page holds 2,267 of those publications, issued between October 2009 and July 2026.
MHRA classes a medicines recall by the hazard the defect presents: Class 1 life-threatening or serious, Class 2 could cause illness or mistreatment, Class 3 unlikely to cause harm, and Class 4 a caution in use rather than a recall, with the product staying available. A device notice is published as Device Safety Information, or, until 2021, as a Medical Device Alert.
What is not here. We hold each publication's title, type, date and link, not its text: read the alert on GOV.UK for the affected products and the actions MHRA asks for. An alert names a medicine or device and a clinical audience, not an organisation, so no alert on this page is linked to an NHS trust or other responsible body. The weekly “Field Safety Notices” pages are MHRA's own index of the notices manufacturers issued that week, not single alerts, and are counted separately above.