Field Safety Notices: 27 September to 01 October 2021
A weekly index of the field safety notices manufacturers issued that week.
Source · Drug & device safety alerts
MHRA Drug & Device Safety Alerts
1,501 individual alerts
447 medicines recalls & defect notices
766 weekly / monthly index pages
Oct 2009 – Jul 2026
Drug safety updates, medicines recalls, device safety information and field safety notices published by the Medicines and Healthcare products Regulatory Agency. Source: MHRA alerts and recalls on GOV.UK.
Showing 2,267 publications of 2,267
Company led medicines recall: Glucose 10%w/v 10ml injection (unlicensed medicine) and Trometamol 7%w/v injection 5mL (unlicensed medicine)
A recall the marketing authorisation holder initiated, published by MHRA.
Class 2 Medicines Recall: Accord-UK Ltd (Trading style: NorthStar), LEVOTHYROXINE TABLETS BP 50 micrograms EL (21)A/23
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Field Safety Notices: 20 to 24 September 2021
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices: 13 to 17 September 2021
A weekly index of the field safety notices manufacturers issued that week.
COVID-19 vaccines and medicines: updates for September 2021
An article in MHRA's monthly Drug Safety Update bulletin.
Letters and medicine recalls sent to healthcare professionals in August 2021
A periodic index page listing other alerts and letters, not a single alert.
Topical corticosteroids: information on the risk of topical steroid withdrawal reactions
An article in MHRA's monthly Drug Safety Update bulletin.
Class 2 Medicines Recall: SANTEN Oy (trading as Santen UK Limited), IKERVIS 1 mg/mL eye drops, emulsion, EL (21)A/22
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Field Safety Notices: 6 to 10 September 2021
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Medicines Defect Information, Rosuvastatin 5 mg, 10 mg, 20 mg and 40 mg film-coated tablets (EL (21)A/21)
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Field Safety Notices: 30 August to 3 September 2021
A weekly index of the field safety notices manufacturers issued that week.
Medical device alerts archived in September 2021
A periodic index page listing other alerts and letters, not a single alert.
Field Safety Notices: 23 to 27 August 2021
A weekly index of the field safety notices manufacturers issued that week.
Class 2 Medicines Recall: Rosemont Pharmaceuticals Limited, Metformin Hydrochloride 500mg/5ml Oral Solution, PL 00427/0139, EL (21)A/20
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Field Safety Notices: 16 to 20 August 2021
A weekly index of the field safety notices manufacturers issued that week.
COVID-19 vaccines: updates for August 2021
An article in MHRA's monthly Drug Safety Update bulletin.
Field Safety Notices: 9 to 13 August 2021
A weekly index of the field safety notices manufacturers issued that week.
Letters and medicine recalls sent to healthcare professionals in July 2021
A periodic index page listing other alerts and letters, not a single alert.
Field Safety Notices: 2 to 6 August 2021
A weekly index of the field safety notices manufacturers issued that week.
Class 2 Medicines Recall: Various Marketing Authorisation Holders and parallel distributor companies, Irbesartan-containing products, EL (21)A/19
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Field Safety Notices: 26th to 30th July 2021
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices: 19 to 23 July 2021
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Medicines Defect Information, Amoxicillin 500 mg/ 5 ml Powder for oral suspension, (PL 25298/0248), EL (21)A/18
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Field Safety Notices: 11 to 16 July 2021
A weekly index of the field safety notices manufacturers issued that week.
Class 4 Medicines Defect Information, Sevredol 10 mg and 20mg tablets, (PL 16950/0063, PL 16950/0064), EL (21)A/17
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Field Safety Notices: 5 to 9 July 2021
A weekly index of the field safety notices manufacturers issued that week.
Oral retinoid medicines (isotretinoin▼, alitretinoin▼, and acitretin▼): temporary monitoring advice during coronavirus (COVID-19) pandemic
An article in MHRA's monthly Drug Safety Update bulletin.
Letters and medicine recalls sent to healthcare professionals in June 2021
A periodic index page listing other alerts and letters, not a single alert.
Herbal and homeopathic medicines: reminder to be vigilant for suspected adverse reactions and to report them to the Yellow Card scheme
An article in MHRA's monthly Drug Safety Update bulletin.
COVID-19 vaccines: updates for July 2021
An article in MHRA's monthly Drug Safety Update bulletin.
Chloramphenicol eye drops containing borax or boric acid buffers: use in children younger than 2 years
An article in MHRA's monthly Drug Safety Update bulletin.
Class 4 Medicines Defect Information, Tetralysal 300mg Hard Capsules, (PL 10590/0019), EL (21)A/16
MHRA class: a minor defect; the product stays available with a caution in use, not a recall.
Field Safety Notices: 28 June to 2 July 2021
A weekly index of the field safety notices manufacturers issued that week.
Class 2 Medicines Recall: Kyowa Kirin Limited, Xomolix 2.5 mg/ml solution for injection, EL (21)A/15
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
Company led medicines recall: Morphine Syringe 50mg/50ml (unlicensed medicine) and Magnesium Sulphate 8mmol/20ml infusion (unlicensed medicine)
A recall the marketing authorisation holder initiated, published by MHRA.
Medical devices sterilised by Steril Milano – potential for incomplete sterilisation (DSI/2021/008)
Device Safety Information (DSI): MHRA advice on a device already in use.
Field Safety Notices: 21 to 25 June 2021
A weekly index of the field safety notices manufacturers issued that week.
National Patient Safety Alert: Philips ventilator, CPAP and BiPAP devices: Potential for patient harm due to inhalation of particles and volatile organic compounds (NatPSA/2021/005/MHRA)
A National Patient Safety Alert requires named actions from NHS providers.
Field Safety Notices: 14 to 18 June 2021
A weekly index of the field safety notices manufacturers issued that week.
Atezolizumab (Tecentriq▼) and other immune-stimulatory anti-cancer drugs: risk of severe cutaneous adverse reactions (SCARs)
An article in MHRA's monthly Drug Safety Update bulletin.
CDK4/6 inhibitors (abemaciclib▼, palbociclib▼, ribociclib▼): reports of interstitial lung disease and pneumonitis, including severe cases
An article in MHRA's monthly Drug Safety Update bulletin.
Letters and medicine recalls sent to healthcare professionals in May 2021
A periodic index page listing other alerts and letters, not a single alert.
COVID-19 vaccines: updates for June 2021
An article in MHRA's monthly Drug Safety Update bulletin.
Class 2 Medicines Recall: Bristol Laboratories Limited, Brown & Burk UK Ltd, Teva UK Ltd, Irbesartan-containing and Losartan-containing products, EL (21)A/14
MHRA class: the defect could cause illness or mistreatment, but is not Class 1.
National Patient Safety Alert: Class 1 Medicines Recall Notification: Recall of Co-codamol 30/500 Effervescent Tablets, Batch 1K10121, Zentiva Pharma UK Ltd, due to precautionary risk of causing overdose, NatPSA/2021/004/MHRA
MHRA class: the defect presents a life-threatening or serious risk to health.
Field Safety Notices: 7 to 11 June 2021
A weekly index of the field safety notices manufacturers issued that week.
Company led medicines recall: Noidecs T20/C4 (THC 20%; CBD <4%) Indica Cannabis Flower (unlicensed medicine) and Noidecs T20/C4 (THC 20%; CBD <4%) Sativa Cannabis Flower (unlicensed medicine)
A recall the marketing authorisation holder initiated, published by MHRA.
Field Safety Notices: 31 May to 4 June 2021
A weekly index of the field safety notices manufacturers issued that week.
Field Safety Notices: 24 to 28 May 2021
A weekly index of the field safety notices manufacturers issued that week.
About this source
Individual alerts by type
Read the chart values
| Alert type | Individual alerts |
|---|---|
| Drug Safety Update | 713 |
| Class 1 Medicines Recall | 6 |
| Class 2 Medicines Recall | 159 |
| Class 3 Medicines Recall | 68 |
| Class 4 Medicines Defect Information | 179 |
| Company-Led Medicines Recall | 35 |
| Device Safety Information | 21 |
| Medical Device Alert | 40 |
| National Patient Safety Alert | 11 |
| MHRA Safety Roundup | 16 |
| Unclassified | 253 |
The MHRA regulates medicines and medical devices in the UK and publishes safety communications on GOV.UK in two streams: the monthly Drug Safety Update bulletin, and Alerts and recalls for drugs and medical devices. This page holds 2,267 of those publications, issued between October 2009 and July 2026.
MHRA classes a medicines recall by the hazard the defect presents: Class 1 life-threatening or serious, Class 2 could cause illness or mistreatment, Class 3 unlikely to cause harm, and Class 4 a caution in use rather than a recall, with the product staying available. A device notice is published as Device Safety Information, or, until 2021, as a Medical Device Alert.
What is not here. We hold each publication's title, type, date and link, not its text: read the alert on GOV.UK for the affected products and the actions MHRA asks for. An alert names a medicine or device and a clinical audience, not an organisation, so no alert on this page is linked to an NHS trust or other responsible body. The weekly “Field Safety Notices” pages are MHRA's own index of the notices manufacturers issued that week, not single alerts, and are counted separately above.