Source · HSSIB Patient Safety Investigation

Unintentional overdose of paracetamol in adults with low bodyweight

HSSIB’s introductionThis investigation explores the prescription of oral paracetamol in adult inpatients who, on admission to hospital, have low bodyweight (less than 50kg).
Published 18 March 2022 Launched 8 April 2021 Published HSIB Legacy
Medication

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Indexed content

3 observations

Safety Observations

3 total
Observation 1 Observation
It may be beneficial for electronic prescribing and medication administration systems to include an alert for oral paracetamol that prompts documentation of a patient’s weight and consideration of the risk of liver toxicity when their weight is less than 50kg.

Source: Unintentional paracetamol overdose in adult inpatients with low bodyweight ↗

Observation 2 Observation
It may be beneficial for the evidence on oral paracetamol and low bodyweight to be reviewed by the relevant national bodies to reach a consensus and agree standardised prescribing guidance.

Source: Unintentional paracetamol overdose in adult inpatients with low bodyweight ↗

Observation 3 Observation
It may be beneficial for available technological solutions, such as beds with built-in scales, to be used to weigh patients. However, the cost of such equipment makes its widespread adoption within the NHS challenging.

Source: Unintentional paracetamol overdose in adult inpatients with low bodyweight ↗