Source · Prevention of Future Deaths

Annette Charlton

Ref: 2015-0009 Date: 9 Jan 2015 Coroner: Louise Hunt Area: Birmingham & Solihull Responses identified: 1 / 6 View PDF

Pharmaceutical manufacturers are producing medications in almost identical packaging, which significantly increases the risk of dispensing errors and poses a serious threat to patient safety.

Date 9 Jan 2015
56-day deadline 6 Mar 2015 est.
Responses identified 1 of 6
Hospital Death (Clinical Procedures and medical management) related deaths

Coroner's concerns

AI summary
Pharmaceutical manufacturers are producing medications in almost identical packaging, which significantly increases the risk of dispensing errors and poses a serious threat to patient safety.
View full coroner's concerns
_ (1) Manufacturers are able to produce medication in almost identical boxes which is likely to contribute to dispensing errors and potentially patient deaths.

Responses

1 respondent
Crescent Pharma Limted
14 Jan 2015 PDF
Action Planned

Crescent Pharma has scheduled a meeting with the MHRA to discuss packaging redesign and the use of colour to differentiate products and strengths, after their request to do so in May 2014. Agreement of design and product range colour chart will lead to the creation of new artwork for all Crescent products, submission for MHRA approval and co-ordination of new artwork introduction after MHRA approval. (AI summary)

View full response
Dear Mrs Hunt We acknowledge receipt of the Regulation 28 form: Report to Prevent Future deaths_ Reqaaiua the issue of packaging similarity, Crescent has scheduled a meeting with the MHRA on the January 2015 to discuss packaging redesign and use of colour to differentiate between different products and strengths, after their request to do so in
2014. Agreement of design and product range colour chart will lead to the creation of new artwork for all Crescent products, submission for MHRA approval and co-ordination of new artwork introduction after MHRA approval. We are unable to provide a timeline for project completion currently: Crescent are therefore committed to revising product artwork to help minimise pharmacist error, caused by the failure to verify product identity during dispensing: this answers the request to provide a response to the report provided.

Report sections

Investigation and inquest
On 7lh October 2014 commenced an investigation into the death of Annette Charlton aged 75. The investigation concluded at the end of the inquest on 6'h January 2015. The conclusion of the inquest was natural causes_
Circumstances of the death
The deceased suffered from emphysema and lung Fibrosis requiring continuous oxygen therapy. On 24/09/14 her GP prescribed a course of antibiotics Phenoxymethylpenicillin 250mg: Her husband attended their local pharmacy: She was inadvertently dispensed Naproxen 250mg: On 27/09/14 she was admitted to Queen Elizabeth Hospital Birmingham short of breath. They realised the error in the medication and prescribed antibiotics. She died on 28/09/14_ The cause of death following post mortem examination was confirmed as end stage pulmonary fibrosis and bronchiectasis. Neither the pathologist; nor a Professor from Queen Elizabeth Hospital Birmingham were able to say that the in antibiotics had caused or contributed to the death; Both were able to confirm that the naproxen had not caused the death_ The dispensing error occurred as the 2 tablets were in almost identical looking boxes and made by the same manufacturer. The Naproxen had been put on the Phenoxymethylpenicillin shelf by mistake. A further mistake had occurred when the pharmacists failed to spot the wrong medication had been chosen: attach a colour copy of the medication boxes to show the similarity. heard evidence at the inquest that this was a national problem namely companies packaging medication in almost identical boxes which meant dispensing errors had become "very common issues" Please note the pharmacist in question has already taken remedial action and introduced new process and procedures within his pharmacy to avoid similar events_ and very delay drug
Action should be taken
In my opinion action should be taken to prevent future deaths and believe you ANDIOR your organisation has the power to take such action.

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Report details

Reference
2015-0009
Date of report
9 January 2015
Coroner
Louise Hunt
Coroner area
Birmingham & Solihull

Responses identified

Responses identified 1 of 6
5 responses not yet linked

Organisations named in PFD reports are normally expected to respond within 56 days. Deadline: 6 Mar 2015 (estimated).

Sent to

Crescent Pharma Ltd
Department of Health and Social Care
General Pharmaceutical Council
Medicines and Healthcare products Regulatory Agency
NHS England
Royal Pharmaceutical Society

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