Source · Prevention of Future Deaths

Robert Stevenson

Ref: 2023-0180 Date: 7 Jun 2023 Coroner: Martin Fleming Area: West Yorkshire (Western) Responses identified: 0 / 1 View PDF

Prescribing doctors may be unaware of a rare potential link between Ciprofloxacin/Quinolone antibiotics and suicidal behaviour, especially in depressed patients. Guidelines should be reviewed to increase awareness and mitigate this risk.

Date 7 Jun 2023
56-day deadline 2 Aug 2023 est.
Responses identified 0 of 1
Alcohol, drug and medication related deaths Suicide (from 2015)

Coroner's concerns

AI summary
Prescribing doctors may be unaware of a rare potential link between Ciprofloxacin/Quinolone antibiotics and suicidal behaviour, especially in depressed patients. Guidelines should be reviewed to increase awareness and mitigate this risk.
View full coroner's concerns
During the inquest I was referred by Mr Stevenson’s treating urologist to published literature relating to Ciprofloxacin and Quinolone antibiotics and a potential rare link to suicide behaviour in patients, although I found on the balance of probabilities that it remained unclear that he was suffering from this side effect, it remained possible for this to be the case. • I heard evidence to suggest that the prescribing doctor did not reference this side effect at the time of issuing the prescription to Mr Stevenson, since it was not in accord with current advice.
• I also heard evidence to suggest that prescribing doctors may not be fully aware of this rare side effect, and that patient’s suffering from depression may be more vulnerable to it.
• I am therefore concerned that this potential risk has not been given sufficient emphasis and I would ask you to consider the appropriateness of reviewing the current guidelines as to the dispensation of the drug to patients by clinicians and increasing the awareness of the side effect in order to monitor and mitigate the risks.

Report sections

Investigation and inquest
On 22/06/22 I opened an inquest into the death of Robert Newton Stevenson who, at the date of his death was aged 63 years old. The inquest was resumed and concluded on 25/5/23. I found that the cause of death to be: ­ 1a. asphyxia (hanging) I arrived at a narrative conclusion:­ Robert Newton Stevenson intended to take his own life when the balance of his mind was disturbed.
Circumstances of the death
Mr Stevenson was a 63 year old gentleman who was a very respected and experienced Consultant Cardiologist and General Physician at Huddersfield Royal Infirmary, who resigned his post in May 2022 to enter full retirement. On 6/5/22 he was referred to the urology department for the investigation of possible prostate cancer, when a decision was also made to consult a private Consultant Urologist. In order to relieve his symptoms of prostatitis and to make him ready for an investigative biopsy, he was prescribed Ciprofloxacin on 19/5/22 at a dose of . He had no previous history of depression or mental health problems. Subsequently on the morning of 30/5/22 Mr Stevenson left his home address on his own for his usual walk. He had not previously given any indications to his family for them to be concerned for him. Thereafter at approximately 12.30pm his wife received a Facebook message from Mr Stevenson to indicate that he had left a note under the pillow of his bed. The note was found to be uncharacteristically confused and illogical given his reference to his baseless concerns that he may have developed AIDs after taking a HIV tester kit he had previously bought on line. Concerns were raised for his welfare, and this trigged an intensive police and family search of the surrounding area. Subsequently, Mr Stevenson was found hanging

Upon the arrival of the paramedics, although resuscitative attempts were made, it was confirmed very sadly that he had passed away.
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Bayer PLC

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Report details

Reference
2023-0180
Date of report
7 June 2023
Coroner
Martin Fleming
Coroner area
West Yorkshire (Western)

Responses identified

Responses identified 0 of 1
1 response not yet linked

Organisations named in PFD reports are normally expected to respond within 56 days. Deadline: 2 Aug 2023 (estimated).

Sent to

Medicines & Healthcare products Regulatory Agency

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